Reference

Coenzyme Q10 [Ubiquinone] phytosome phospholipid complex

Coenzyme PQQ [Pyrolloquinoline quinone] disodium salt

Spermidine trihydrochloride

Vitamin K2 MK-7 [Menaquinone-7] (Bacillus subtilis var. natto-derived postbiotic)

Japanese wasabi (Wasabia japonica) extract (root) [2% isothiocyanates]

Japanese pagoda tree (Sophora japonica) extract (flower) [95% quercetin]

Chelation is a process designed to support optimal absorption in the digestive tract—chelated minerals have been bound to amino acids or other organic compounds to form a more stable complex. DM-02™ delivers zinc, copper, manganese, molybdenum, and chromium in chelated forms.

Research suggests that certain chelated forms—such as glycinate or bisglycinate chelates—may be more bioavailable than some traditional mineral salts (like oxides or sulfates), particularly under conditions where absorption may be impaired. Chelated minerals are also less likely to interact with other compounds in the gut that can inhibit absorption, such as phytates or competing minerals. This can be particularly important in multinutrient formulas, where multiple minerals are consumed at once.*

Wasabi (standardized to 2% isothiocyanates) is derived from Wasabia japonica, a plant traditionally consumed in Japan for over a millennium. The pungent compounds responsible for wasabi's characteristic heat are isothiocyanates—bioactive sulfur-containing molecules also found in cruciferous vegetables like broccoli and mustard. Preclinical research has demonstrated that specific wasabi-derived isothiocyanates, including 6-methylsulfinylhexyl isothiocyanate (6-MSITC), possess broad-spectrum properties, capable of favoring the growth of beneficial microbes over unwanted microbial populations.

These effects are believed to be mediated through modulation of bacterial quorum sensing and disruption of microbial cell membranes. In vitro and animal studies also suggest potential inflammatory-balancing, antioxidant, and detoxification-supporting properties, attributed to activation of phase II enzymes via the Nrf2 pathway, a key cellular defense mechanism.*

Most supplements, fruits, vegetables, milk-derived proteins, and natural products carry some level of heavy metals. These can be very difficult to completely eliminate from the diet, due to their uptake from the surrounding air, water, and soil. In California, food and natural products are regulated under Proposition 65 (the Safe Drinking Water and Toxic Enforcement Act of 1986), which sets ‘safe harbor levels’ for chemicals known to the state to potentially cause cancer or reproductive toxicity.

Seed abides by these stringent regulations and tests all products for the four main categories of heavy metals: Arsenic, Cadmium, Lead, and Mercury.

DM-02™ is tested for over 500 pesticide residues using gas chromatography with tandem mass spectrometry at third-party accredited laboratories. PM-02™ is intentionally subjected to testing for the ubiquitous pesticide, glyphosate, as well as its breakdown product—AminoMethylPhosphonic Acid (AMPA)—using liquid chromatography with tandem mass spectrometry. This rigorous testing protocol ensures adherence to our strict quality standards.

The full list of pesticides tested may be viewed here.