Dr. Geoffrey Preidis is an Assistant Professor of Pediatrics at Baylor College of Medicine and Texas Children’s Hospital. He specializes in pediatric gastroenterology, hepatology, and nutrition with a special interest in neonatal gastroenterology. His laboratory seeks to define how early-life malnutrition and changes in the gut microbiome influence metabolism, intestinal, and liver functions.

His work has received funding from the National Institutes of Health, Global Probiotics Council, Thrasher Research Fund, NASPGHAN Foundation/Nestle Nutrition Research, American Neurogastroenterology and Motility Society, and American Gastroenterological Association.

Dr. Preidis graduated from medical school at Baylor College of Medicine, where he also received a PhD in Translational Biology and Molecular Medicine. He is board certified in pediatrics and is an active member of the American Gastroenterological Association, serving on the Center for Gut Microbiome Research and Education Scientific Advisory Board.

His most recent work is published in PLoS Neglected Tropical Diseases, Journal of Nutritional Biochemistry, Journal of Nutrition, Therapeutic Advances in Gastroenterology, Gut Microbes, and Journal of Clinical Investigation.

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Key Publications:

Preidis G A, Kim K H, Moore D D. “Nutrient-sensing nuclear receptors PPARα and FXR control liver energy balance.” J Clin Invest. 127:1193-1201, 2017 April 3. Web 2017 Mar 13. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/28287408. DOI: 10.1172/JCI88893

Velly H, Britton R A, Preidis G A. “Mechanisms of cross-talk between the diet, the intestinal microbiome, and the undernourished host.” Gut Microbes. 8:98-112, 2017 March 4. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/27918230. DOI: 10.1080/19490976.2016.1267888

Preidis G A, Chumpitazi B P, Shulman R J. “The microbiome in neurogastroenterology.” Pediatric Neurogastroenterology.; Springer International Publishing, Switzerland(Faure C, Thapar N, Di Lorenzo C, Eds.) pages: 53-70, 2017. Accessed 2018 June 4. https://www.springer.com/us/book/9783319432663.

Preidis G A, Ajami N J, Wong M C, Bessard B C, Conner M E, Petrosino J F. “Microbial-derived metabolites reflect an altered intestinal microbiota during catch-up growth in undernourished neonatal mice.” J Nutr. 146:940-8, 2016 May. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/27052538. DOI: 10.3945/jn.115.229179

Preidis G A, Ajami N J, Wong M C, Bessard B C, Conner M E, Petrosino J F. “Composition and function of the undernourished neonatal mouse intestinal microbiome.” J Nutr Biochem. 26(10):1050-7, 2015 Oct. Web 2015 May 15. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/26070414. DOI: 10.1016/j.jnutbio.2015.04.010

Ahmed S, Kim M H, Dave A C, Sabelli R, Kanjelo K, Preidis G A, Giordano T P, Chiao E, Hosseinipour M, Kazembe P N, Chimbwandira F, Abrams E J. “Improved identification and enrolment into care of HIV-exposed and -infected infants and children following a community health worker intervention in Lilongwe, Malawi.” J Int AIDS Soc. 7;18:19305, 2015 Jan. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/25571857 . DOI: 10.7448/IAS.18.1.19305

Finocchario-Kessler S, Gautney B J, Khamadi S, Okoth V, Goggin K, Spinler J K, Mwangi A, Kimanga D, Clark K F, Olungae H D, Preidis G A, HITSystem Team. “If you text them, they will come: using the HIV infant tracking system to improve early infant diagnosis quality and retention in Kenya.” AIDS. 28 Suppl 3:S313-21, 2014 Jul. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/24991904 . DOI: 10.1097/QAD.0000000000000332

Perry S H, Swamy P, Preidis G A, Mwanyumba A, Motsa N, Sarero H N. “Implementing the Jadelle implant for women living with HIV in a resource-limited setting: concerns for drug interactions leading to unintended pregnancies.” AIDS 13;28(5):791-3, 2014 Mar. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/24401645. DOI: 10.1097/QAD.0000000000000177

Preidis G A, Keaton M A, Campeau P M, Bessard B C, Conner M E, Hotez P J. “The undernourished neonatal mouse metabolome reveals evidence of liver and biliary dysfunction, inflammation, and oxidative stress.” J Nutr. 144(3):273-81, 2014 Mar. Web 2013 Dec 31. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/24381221. DOI: 10.3945/jn.113.183731

McCollum E D, Preidis G A, Maliwichi M, Olson D, McCrary L M, Kazembe P N, Horst Cv, Hoffman I, Hosseinipour M C. “Clinical versus rapid molecular HIV diagnosis in hospitalized African infants: a randomized controlled trial simulating point-of-care infant testing.” J Acquir Immune Defic Syndr. 66(1):e23-30, 2014 May 1. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/24326604. DOI: 10.1097/QAI.0000000000000080.

Kim M H, Ahmed S, Preidis G A, Abrams EJ, Hosseinipour M C, Giordano T P, Chiao E Y, Paul M E, Bhalakia A, Nanthuru D, Kazembe P N. “Low rates of mother-to-child HIV transmission in a routine programmatic setting in Lilongwe, Malawi.” PLoS One. 8(5):e64979, 2013 May 31. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/23741437. DOI: 10.1371/journal.pone.0064979

Olson D, Preidis G A, Milazi R, Spinler J K, Lufesi N, Mwansambo C, Hosseinipour M C, McCollum E D.
“Task shifting an inpatient triage, assessment and treatment programme improves the quality of care for hospitalised Malawian children.” Trop Med Int Health 18(7):879-86, 2013 Jul. https://www.ncbi.nlm.nih.gov/pubmed/23600592 . DOI: 10.1111/tmi.12114

Preidis G A, Saulnier D M, Blutt S E, Mistretta T A, Riehle K P, Major A M, Venable S F, Finegold M J, Petrosino J F, Conner M E, Versalovic J. “Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine.” FASEB J. 26(5):1960-9, 2012 May. Accessed 2018 June 4. https://www.ncbi.nlm.nih.gov/pubmed/22267340 . DOI: 10.1096/fj.10-177980