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The Daily Synbiotic

What is the Daily Synbiotic?

Seed’s Daily Synbiotic combines clinically-verified, naturally-occurring probiotics strains (not found in yoghurt, most supplements, or fermented foods and beverages) with a new class of non-fermenting prebiotic compounds (built around a patented whole fruit extract) sourced from Indian pomegranate and Scandinavian chaga mushroom and pine bark. It’s available in both female (24 strains) and male (20 strains) formulations.

It’s the first to take a Microbe-Systems Approach with strain-specific benefits beyond digestive health, including heart health, skin health, gut immune function, reproductive health, gut barrier integrity, and oxidative stress. The female formulation is also the first probiotic with strains that synthesize folate and increase production in the body.

Who should take the Daily Synbiotic?

The Daily Synbiotic is meant for humans ages 18+.

Why should I take the Daily Synbiotic?

You are home to a community of 38,000,000,000,000 microorganisms (mostly bacteria) that live in and on you. They perform critical functions like digesting food, managing inflammation, and synthesizing key vitamins, metabolites and neurotransmitters. This is your microbiome.

However, modern living disturbed the balance of this ecosystem. Antibiotic overuse combined with alcohol, sugar, tobacco, disrupted sleep, city-living, decreased breastfeeding, stress, poor diet, and other environmental factors, have depleted the diversity and richness of our microbiomes and impacted our health.

This goes beyond simple digestive issues. The first of its kind, our Daily Synbiotic delivers a range of clinically-verified, core benefits to the gastrointestinal system, which in-turn, influences gut immune, metabolic, cardiovascular, skin, urogenital, and systemic health.

What does the Daily Synbiotic do?

The Daily Synbiotic has been clinically-studied to provide benefits around gastrointestinal function, gut barrier integrity, cardiovascular health, metabolism and energy production, gut immune function, and oxidative stress. The female formulation also contains strains that increase folate production (folate plays a critical role in fertility and pregnancy) and support dermatological health.

Why is the Daily Synbiotic different from other probiotics?

Next-generation probiotics

A proprietary formulation comprised of 24 strains characterized at academic institutions and research partners in Italy, Spain, Belgium, US, and Japan. Where other probiotics incorporate strains from animal or soil, we only select strains that are naturally occurring in the human body. Our benefits are validated by 23+ strain-specific clinical studies and Seed’s own clinical research.

Nested Capsule Technology + Patented algae delivery system

Bacteria are fragile—they are sensitive to light, temperature, and moisture. In many cases, they hardly survive the trip from manufacturer to store shelf, much less your digestive process (think stomach acids and bile). We took care of this. Our exclusive nested capsule technology and patented algae delivery system ensure bacteria stay alive and viable through digestion and make it to your colon, where their work begins. This also means there’s no synthetic or chemical coating, and that the Daily Synbiotic is shelf stable for 18 months and requires no refrigeration.

Is the Daily Synbiotic gluten-free? Vegan?


The Daily Synbiotic is free from: Dairy • Gluten • Corn • Soy • GMOs • Binders • Fillers • Flowing Agents • Excipients • Preservatives

It adheres to the following diets: Vegan • Vegetarian • Ketogenic

Does the Daily Synbiotic contain GMOs?

The Daily Synbiotic does not contain genetically modified organisms, and as such, is classified as non-GMO.

However, as a company grounded in science, we also want to ensure that labeling our product as non-GMO doesn’t contribute to blanket fears and misunderstandings of GMOs in general. Just as we aim to steward the term probiotics, there are scientists and researchers working to steward the field of synthetic biology and bioengineering towards applications that can save many lives (i.e. insulin—which without genetic engineering we would not be able to meet the demand for) and ensure humanity’s survival on this planet, while protecting the planet itself (i.e. genetically engineered bacteria that can create biomaterials to replace plastic or produce biofuels affordably, efficiently, and sustainably).

Like bacteria, GMOs have faced a long and complex history. Like any industry or category, there are those who don’t have the consumer’s best interests in mind, but also those who will relentlessly push for us to use biotechnology responsibly, for the benefit of the planet and its people. Whatever your stance on GMOs, the only way forward is an open mind and open dialogue.

Is the Daily Synbiotic safe to take while pregnant or breastfeeding?

Yes, the Daily Synbiotic is safe to take during pregnancy and while breastfeeding, but as with all new changes during this time, we suggest that you speak with your physician.

Fun company fact: Seed Co-Founders Ara and Raja were introduced when Ara was pregnant. Her journey through pregnancy and breastfeeding (with Raja’s guidance and education) inspired their collaborative vision for Seed.

Are there any side effects when taking the Daily Synbiotic?

Just like with any new diet, product, or change, your body may experience a temporary acclimation period. In the first 3-5 days of taking your Daily Synbiotic, you may feel some gastrointestinal discomfort, abdominal tightness, mild nausea, or changes in your stool. This is very normal.

An immediate physiological reaction is a sign that our probiotics are viable and attuning to your system as they move through your gastrointestinal tract. Any discomfort should subside within the first one to two weeks.

As you begin Seeding, we suggest this acclimation protocol:

Day 1-3
Take 1 capsule daily.

Day 4
When you’re ready, increase to full dose of 2 capsules at once, daily.

We’re here for any questions—[email protected]

I'm transgender and transitioning, or intersex, which formulation is right for me?

If you have a body, you have a microbiome. No matter your sex, gender, sexual preference, or ethnicity, health is a human issue and health is inclusive.

Our Daily Synbiotic is distinguished by sex (female / male), not by gender (women / men). The female formulation contains strains that increase folate production (folate plays a critical role in fertility and pregnancy) and support dermatological health. The male formulation contains two unique strains that emerged from a clinical study conducted in males only, evaluating muscle recovery after high intensity exercise.

That being said, we also recognize that there is a large population of intersex people who are born with physical sex characteristics that don’t ascribe to binary female or male, as well as some transgender humans who are in transition to another sex.

Through many conversations with friends in the transgender and intersex communities, journalists, writers, and activists stewarding these important conversations, we’ve learned that some prefer we use language like ‘person with predominantly testosterone’ and ‘people with predominantly estrogen’. Given our commitment to comply with science and clinical research, we use female / male language consistent with how research is conducted today, though we will always strive to be most sensitive and empathic in our language and approach.

Both our formulations are safe to take, regardless of your sex or gender. If you need more specifics to determine which formulation is right for you, please don’t hesitate to reach out ([email protected]).

These conversations matter. Let’s keep having them in an open, inclusive, and safe way. We welcome any and all feedback and ideas about what else we can do or think about to better meet the needs of all humans.

How to Use

How do I take the Daily Synbiotic?

Adults—take 2 capsules daily, all at once. Preferably on an empty stomach to limit exposure to digestive enzymes and bile salts.

What is the serving size?

2 capsules.

When will I feel something?

Everyone’s body is different, and the benefits you ‘feel’ (reduced bloating, more regular bowel movements, higher energy) are often just the most visceral ones.

You may feel results in as a little as 24-48 hours due to localized benefits like improved digestion. Other longer term benefits like cardiovascular health and metabolic function may take longer, or you may not notice anything at all. That’s completely normal. As long as you continue your daily intake, those beneficial microbes are doing their work inside to program, sustain, and enhance your health.

Can I take this with other supplements?

Yes, the Daily Synbiotic is safe to take with other supplements.

Should I take with food?

We recommend taking the Daily Synbiotic on an empty stomach to limit exposure to digestive enzymes and bile salts. However, you know your body best—if it’s more comfortable for you to take with food, please feel free.

What happens if I take more than the recommended dose per day?

It’s safe to take more than the recommended dosage, though there is not necessarily any added benefit to do so.

What happens if I take the Daily Synbiotic when it's expired?

It’s safe to take if expired, however, we only guarantee potency and efficacy up until the expiration date. If your product is expired, please let us know and we will replace it free of charge.

Can I keep these in my pill organizer?

We don’t recommend this, as bacteria are sensitive to light. Our jar is designed to protect the Daily Synbiotic so capsules should be stored in it. However, every first purchase comes with a complimentary travel vial, which holds 14 capsules (1 week’s worth), which is also safe for transporting your Daily Synbiotic on the go.

What happens if I miss a dose? Or a few doses?

There’s no harm if you miss a day, or even if you miss a few. But for optimal results, daily intake is encouraged.

This is because our probiotics are transient microbes, which journey through your colon (where the majority of your microbiome resides) to activate systemic benefits through programmed interactions with your existing bacteria and your body. This is why continuous intake is important—it’s the clinically-verified dosage to optimize for the most impact.

Do I need to refrigerate my Daily Synbiotic?

The short answer is no. No refrigeration necessary.

It’s a question we receive often, since many probiotics are sold in the refrigerated section at grocery stores and retailers. However, contrary to perishable food products, refrigeration doesn’t mean ‘freshness’ or superiority. In fact, if a probiotic does not survive at ambient temperature outside of the refrigerator, it can reflect weak stability of the product, low viable organism count, or inadequate overages in formulation.

Our probiotic strains are stable at ambient temperature (up to 79° F). If your home is consistently warmer for extended periods, consider refrigerating in an oxygen tight container to avoid exposure to moisture.


Do I have to sign up for a subscription?

Yes. We believe that probiotics and prebiotics, alongside diet, nutrition, exercise, and lifestyle, are cornerstone tools to building foundational health. Clinical research shows that continuous, daily intake is the best way to get the most out of your synbiotic. By signing up for a subscription, you’ll easily be able to build the Daily Synbiotic into your routine.

But we want you to feel good about what you’re taking. That’s why we want you to try the Daily Synbiotic, risk-free for 30 days. You can also reschedule or cancel your subscription easily from your account at any time.

What does a subscription to the Daily Synbiotic include?

Your monthly subscription includes a 30-day supply. Your first month’s shipment is your Welcome Kit. It includes a reusable glass jar holding your first month’s supply, some Seed reading materials, and a free travel vial that holds a week’s worth of your Daily Synbiotic.

Why does my second month's shipment look different from the first?

Cool—you’ve met our sustainable refill system!

The planet is really important to us, so we’re constantly looking for materials that are sustainable and Earth-friendly, without sacrificing the safety and protection of your Daily Synbiotic. Our jars are made of glass, which is infinitely recyclable, but the less we put out there, the better. That’s why we ask you to keep your reusable glass jar and send you monthly refills instead.

All shipments after your first will come in a certified home-compostable, bio-based pouch that is oxygen and moisture resistant, while being planet-safe. It’s easy—just open the pouch and refill your jar.

How do I sign up for a subscription?

To order online, simply visit our Product page, select Male or Female Daily Synbiotic, and proceed to checkout.

Why is the Male Daily Synbiotic only available for preorder?

Our Male Daily Synbiotic is currently backordered and is expected to ship by the end of October. You may preorder yours here. We’re here for any questions—[email protected]

I'm having trouble logging into my account.

Apologies for any confusion—we’ve migrated to a new platform so we can work better for you (and your microbes). To ensure your existing account is synced with our new platform, kindly reactivate—this will allow you to manage your subscription, payment information, and shipment schedule.

Simply reactivate your account and follow the short prompts. You’ll only need to do this once. We’re here to help—[email protected] if you have any questions.

How do I cancel my subscription?

You may cancel your subscription in your account or by contacting SeedCare. Sorry to see you go—we’ll miss you (and your microbes).

I lost/broke my glass jar. How can I get a replacement?

No worries, it happens! Just get in touch with us—[email protected], and we’ll ship you a new one right away.

How do I review my orders, order history, or tracking information?

You’ll receive an order confirmation email when you first sign up and a shipping confirmation email when your product is ready to ship. You can also view all of this information in your account or by contacting SeedCare.

How do I update my shipping and billing information?

You can update your shipping and billing information in your account or by contacting SeedCare.

I'm traveling—is there a way to put my subscription on hold?

Of course! You can go into your account and reschedule your upcoming shipment for any date in the future. Once you do, we’ll automatically update any further monthly shipments.

Don’t forget to pack your travel vial! 😉

Shipping + Billing

What payments do you accept?

Visa, MasterCard, American Express, Discover, and PayPal. We unfortunately currently cannot accept cash, checks, money orders, bitcoin, or hugs. 🙂

How much is shipping?

Shipping to the US: free

Shipping internationally: $10 flat rate (USD)

If you live outside of the US, after your first month you may continue with monthly refills shipped flat rate ($10 USD), or enroll in our Sustainable Transport Program for 90-day refills, billed every 3 months, shipped free.

You help us reduce shipping frequency and we cover your shipping (save $120 USD / year). Together, we can refill, not land-fill.

How much are returns?

There’s no need to send your Daily Synbiotic back to us for a return. We have a 30-day risk-free guarantee, meaning, if you decide in the first 30 days that the Daily Synbiotic is not right for you, we’ll issue a refund for the cost of the product, no questions asked. For all subsequent shipments, you may reschedule or cancel at any time in your account.

Will I be charged sales tax?

Shipping to the US: We are required to collect sales tax for orders shipping to the following states:

New Jersey
New York
North Carolina

All other states are currently tax-free.

Shipping internationally: We ship DDP, meaning duties and taxes are paid up front, at checkout. Our global delivery partner, Passport Shipping, built a state-of-the-art shipping calculator that estimates duties and taxes before you place your first order. We will recalculate duties and taxes monthly, for each refill package. Kindly note, the price will typically remain the same unless there has been a change in your country’s government policy.

When will I be charged for my preorder?

You may see a payment authorization on your card after you preorder your Daily Synbiotic. This is a common bank practice for handling debit and credit card transactions to ensure account authenticity.

A pre-authorization for the purchase amount may occur just before shipping and is the practice within the banking industry of authorizing electronic transactions done with a debit card or credit card, and if requested, holding the amount owed as unavailable either until we clear the transaction (ship you the product) or the hold “falls off.” Debit card authorization holds can fall off your account (thus rendering the balance available again) anywhere from 1-8 days after the transaction date depending on the bank’s policy. Credit card holds may last as long as 30 days, depending on the issuing bank.

If your order was declined, denied, or canceled, this preauthorization will clear on its own (depending on your bank, anywhere from 1-8 business days). If your order is successful, the preauthorization will turn into a charge once your order ships. If your order is delayed for any reason, the preauthorization may clear within a few days then come back as a charge once your order ships.

We do not have the capability to release the bank’s temporary hold on authorized funds. Therefore we cannot be held responsible for the policies of your banking institution regarding the holding of authorized funds. Kindly contact your issuing credit card company or bank directly for more specific information.

Do you ship internationally?

Yes—we currently ship to:

United States (including PO Boxes, U.S. territories, and APO/FPO addresses)
Czech Republic
Hong Kong
New Zealand
South Korea
United Arab Emirates
United Kingdom

When will my package arrive?

Shipping to the US: Your first order should arrive within 3-5 business days after your order ships.

Shipping internationally: Your first order should arrive within 7-14 business days after your order ships.

Once your order ships, we’ll email you a tracking link so you can keep an eye out for it. Subsequent shipments will arrive in time to refill your monthly supply.

When will my credit card be charged?

You are billed each month when your monthly order ships, using the payment method you have on file. This charge will occur approximately every 30 days, unless you cancel.

How can I trust that my saved payment and personal information is secure?

We are a certified PCI DSS compliant service provider. This means we take your security very seriously and never disclose your personal identity or information with anyone. You can read our full Privacy Policy here.

Will my Daily Synbiotic survive being shipped in the heat?

We’ve conducted extensive heat testing on our Daily Synbiotic—after 10 days of constant, 24 hour, 100º F exposure (which is highly unlikely even in the heat of summer), our probiotic bacteria counts and viability exceeded the living cell counts stated on our label. Only with constant exposure to the blazing temperature of 120ºF, continuously over 2 days (48 hours), did the total biopotency of the Daily Synbiotic barely dip below label claim numbers and requirements.

Depending on the temperature of your home (or where you are traveling), kindly follow the recommended storage guidelines.

One of my items arrived damaged. What do I do?

Yikes! So sorry that happened. For defective or damaged items, please reach out to SeedCare—[email protected]—and we’ll ship you a replacement immediately.

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