Why is the DS-01™ only available for preorder?
DS-01™ is only available for preorder, but I’m already a member. Will I still receive my refills?
Yes—your monthly refills will continue to ship regularly.
When will my DS-01™ preorder ship?
We expect to be able to start shipping DS-01™ preorders in the next 1-2 weeks. We will send you an email three days prior to shipment to give you plenty of time to update shipping information, if needed.
When will I be charged for my DS-01™ preorder?
You will be charged for your Welcome Kit at the time you place your preorder—this will reserve your subscription to ensure ongoing monthly refills.
Can COVID-19 spread through packages?
Although the virus can survive for a short period on some surfaces, it is unlikely to be spread from domestic or international mail, products, or packaging. While it is not thought to be the main way the virus spreads, it may be possible to get the virus by touching a surface or object that has the virus on it and then touching your mouth, nose, or possibly eyes. The CDC recommends washing your hands with soap and water for at least 20 seconds or using a hand sanitizer with at least 60% alcohol after collecting mail.
Are you experiencing any shipping delays or disruptions?
Shipping in the US: Many carriers are implementing new processes to mitigate the spread of COVID-19, which is resulting in some delays. You may view operational impacts for our primary carrier here: USPS.
We understand our carrier partners are experiencing a surge in deliveries, so we appreciate your patience should any unforeseen delays occur. If you’d like to move up your shipment to ensure your refill arrives a few days earlier (to get ahead of any potential carrier delays), you may do so in your account or email [email protected] and we’d be happy to help.
Shipping internationally: Local carriers in certain countries are experiencing delays and some closures. We are closely monitoring the situation with our global delivery partner, Passport Shipping, and will notify you immediately of any serious changes, such as ceasing all inbound shipments to your country.
Passport Shipping has compiled a live feed so you may stay informed of updates in your country.
If you have any concerns regarding your shipments, we’re here to help—[email protected].
Is DS-01™ safe to take?
Yes. Our extensive safety measures across our manufacturing chain have not changed—our probiotics are cultured in a sterile solution, in a laboratory setting, and undergo whole-genome sequencing to ensure that they are free of any contaminants.
Additionally, we implement over 50 quality assurance and quality control checkpoints to monitor purity under both US and European protocols (including cGMP + HAACP) throughout the production cycle with no skip-lot testing (this means we test each ingredient batch prior to encapsulation and each batch after manufacture). We also adhere to the highest global regulatory standards and rigorously test beyond what’s required to ensure clinically-studied dosages with demonstrated quality, efficacy, and safety.
Can probiotics like DS-01™ prevent or mitigate the risk of COVID-19?
DS-01™ has not been assessed in any research pertaining to COVID-19. Our product is not intended to diagnose, treat, cure or prevent any disease, including COVID-19. At this time, there is no evidence that any supplements are helpful in reducing the risk of COVID-19.
The WHO and the CDC recommend preventative actions to help reduce the risk of spreading and contracting the disease, such as: frequent hand washing, practicing physical distancing, avoiding face touching, and practicing good respiratory hygiene such as sneezing and coughing into your elbow or a tissue.
As this continues to be a rapidly evolving situation—we recommend staying informed and following local recommendations and regulations provided for your community.
Do you have any resources to learn more about COVID-19?
Yes—if helpful, we’ve worked with our ecosystem of scientists, doctors, and researchers to compile a COVID-19 Highlight on our Instagram that breaks down FAQs, recommendations, resources, and research. We’ll continue to add to this as we learn more from public health and the scientific and medical communities.
DS-01™ Daily Synbiotic
What is DS-01™?
Seed’s DS-01™ combines 24 clinically and scientifically studied probiotic strains (not found in yogurt, most supplements, or fermented foods and beverages) with a non-fermenting prebiotic compound concentrated from Indian pomegranate.
It’s among the first to take a Microbe-Systems Approach with strain-specific benefits beyond digestive health, including skin health, heart health, gut immune function, gut barrier integrity, and micronutrient synthesis. It’s also among the first formulations to include a strain that synthesizes folate and increases production within the body.
Who should take DS-01™?
The DS-01™ is meant for humans ages 18+.
Why should I take the DS-01™?
You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. They perform critical functions like digesting food, managing inflammation, and synthesizing key vitamins, metabolites and neurotransmitters. This is the microbiome.
However, modern living disturbed the balance of this ecosystem. Antibiotic overuse combined with alcohol, sugar, tobacco, disrupted sleep, city-living, decreased breastfeeding, stress, poor diet, and other environmental factors, have depleted the diversity and richness of our microbiomes and impacted our health.
This goes beyond simple digestive issues. The first of its kind, our DS-01™ includes clinically and scientifically studied probiotic strains that deliver core benefits to the gastrointestinal system which, in turn, influence systemic health.
What does the DS-01™ do?
The DS-01™ contains probiotic strains that have been clinically and scientifically studied to provide benefits around gastrointestinal function, skin health, heart health, gut immune function, gut barrier integrity, and micronutrient synthesis. You may access the strain-specific clinical studies associated with each benefit in our Reference Library.
Why is DS-01™ different from other probiotics?
A proprietary formulation comprising of 24 strains characterized at academic institutions and research partners in Italy, Spain, Belgium, US, and Japan. 23 of our strains are human-derived and one strain was isolated from fruit (screened against 400+ strains of the same species) specifically because it has clinically demonstrated the ability to help promote healthy cholesterol levels. Our benefits have been validated in 16 strain-specific, double-blind, placebo-controlled, published human studies as well as 13 in vitro/ex vivo mechanistic studies.
Nested Capsule Technology + Patented algae delivery system
Bacteria are fragile—they are sensitive to light, temperature, and moisture. In many cases, they hardly survive the trip from manufacturer to store shelf, much less your digestive process (think stomach acids and bile). We took care of this. Our exclusive nested capsule technology ensures bacteria stay alive and viable through digestion and make it to your colon, where their work begins. We use a patented algae delivery system to provide additional protection for our most sensitive strains. This also means there’s no synthetic or chemical coating, and that the DS-01™ is shelf-stable for 18 months and requires no refrigeration.
Is DS-01™ compatible with my diet or dietary restrictions?
DS-01™ is free from: Dairy • Gluten • Soy • GMOs • Nuts • Shellfish • Sesame • Glyphosate/AMPA • Binders • Preservatives • 14 classes of allergens defined by European Food and Safety Authority (EFSA)
It adheres to the following diets: Vegan • Vegetarian • Ketogenic • Gluten-Free • Intermittent Fasting.
Does DS-01™ contain GMOs?
DS-01™ does not contain genetically modified organisms, and as such, is classified as non-GMO.
However, as a company grounded in science, we also want to ensure that labeling our product as non-GMO doesn’t contribute to blanket fears and misunderstandings of GMOs in general. Just as we aim to steward the term probiotics, there are scientists and researchers working to steward the field of synthetic biology and bioengineering towards applications that can save many lives (i.e. insulin—without genetic engineering we would not be able to meet demand) and ensure humanity’s survival on this planet, while protecting the planet itself (i.e. genetically engineered bacteria that can create biomaterials to replace plastic or produce biofuels affordably, efficiently, and sustainably).
Like bacteria, GMOs have faced a long and complex history. Like any industry or category, there are those who don’t have the consumer’s best interests in mind, but also those who will relentlessly push for us to use biotechnology responsibly, for the benefit of the planet and its people. Whatever your stance on GMOs, the only way forward is an open mind and open dialogue.
Is DS-01™ safe to take while I'm pregnant or breastfeeding?
Yes, the DS-01™ is safe to take during pregnancy and while breastfeeding, but as with all new changes during this time, we suggest that you also speak with your physician.
Fun company fact: Seed Co-Founders Ara and Raja were introduced when Ara was pregnant. Her journey through pregnancy and breastfeeding (with Raja’s guidance and education) inspired their collaborative vision for Seed.
Are there any side effects when taking DS-01™?
With any new diet, product, or change, your body may experience a temporary acclimation period. In the first few days of taking your DS-01™, you may feel some gastrointestinal discomfort, abdominal tightness, mild nausea, or changes in your stool. This is very normal.
An immediate physiological reaction is a sign that our probiotics are viable and attuning to your system as they move through your gastrointestinal tract. Any discomfort generally subsides within the first one to two weeks.
As you begin Seeding, we suggest this acclimation protocol:
Take 1 capsule daily.
When you’re ready, increase to the full dose of 2 capsules at once, daily.
We’re here for any questions—[email protected]
How to Use
How do I take DS-01™?
Adults—take 2 capsules daily, all at once. Preferably on an empty stomach to limit exposure to digestive enzymes and bile salts. However, you know your body best—if it’s more comfortable for you to take with food, please feel free to do so.
What is the serving size?
2 capsules, daily.
When will I feel something?
Everyone’s body is different, and the benefits you may ‘feel’ (ease of bloating, more regular bowel movements) are often just the most visceral ones.
Many people feel results in as a little as 24-48 hours due to localized benefits like digestive health support. Other longer term benefits like cardiovascular health and gut immune function may take longer, or you may not notice anything at all. That’s completely normal. As long as you continue your daily intake, those beneficial microbes are doing their work inside to program, sustain, and enhance your health.
Can I take this with other supplements? What about medications?
DS-01™ is safe to take with other supplements.
There are no known contraindications with DS-01™ and any over the counter or prescription medications, though we encourage you to double check with your physician before adding our product to your regimen.
Should I take it with food?
We recommend taking DS-01™ on an empty stomach to limit exposure to digestive enzymes and bile salts. However, you know your body best—if it’s more comfortable for you to take with food, please feel free.
What happens if I take more than the recommended dose per day?
It’s safe to take more than the recommended dosage, though there is not necessarily any added benefit.
What happens if I take DS-01™ when it's expired?
It’s safe to take if expired, however, we only guarantee potency and efficacy up until the expiration date. If your product is expired when you receive your order, please let us know and we will replace it free of charge.
Can I keep these in my pill organizer?
We don’t recommend this, as bacteria are sensitive to light. Our jar is designed to protect your DS-01™, so your capsules should be stored in it. Every first purchase comes with a complimentary travel vial, which holds 14 capsules (1 week’s worth), which is also safe for transporting your DS-01™ on the go.
What happens if I miss a dose? Or a few doses?
There’s no harm if you miss a day, or even if you miss a few. But for optimal results, daily intake is encouraged.
This is because our probiotics are transient microbes, which journey through your colon (where the majority of your microbiome resides) to activate systemic benefits through programmed interactions with your existing bacteria and your body. That’s why continuous, daily intake is important using clinically and scientifically studied strains and dosages.
Do I need to refrigerate my DS-01™?
The short answer is no. No refrigeration necessary.
It’s a question we receive often, since many probiotics are sold in the refrigerated section at grocery stores and retailers. However, contrary to perishable food products, refrigeration doesn’t mean ‘freshness’ or superiority. In fact, if a probiotic does not survive at ambient temperature outside of the refrigerator, it can reflect weak stability of the product, low viable organism count, or inadequate overages in formulation.
Our probiotic strains are stable for 18 months at ambient temperature (up to 79° F). If your home is consistently warmer for extended periods, consider refrigerating in an oxygen tight container to avoid exposure to moisture.
How much is Seed’s DS-01™ subscription?
Each DS-01™ subscription includes a 30-day supply (60 capsules) for $49.99/month—billed and delivered, monthly. We offer free shipping within the US, and a $10 flat rate for international shipments.
Do I have to sign up for a subscription?
Yes. We believe that probiotics and prebiotics, alongside diet, nutrition, exercise, and lifestyle, are cornerstone tools to building foundational health. Clinical research shows that continuous, daily intake is the best way to get the most out of your synbiotic. By signing up for a subscription, you’ll easily be able to build the DS-01™ into your routine.
But we want you to feel good about what you’re taking. That’s why we want you to try the DS-01™, risk-free for 30 days. You may also reschedule or cancel your subscription easily from your account at any time.
What does my subscription to DS-01™ include?
Your monthly subscription includes a 30-day supply of DS-01™. Your first month’s shipment is your Welcome Kit. It includes a reusable glass jar holding your first month’s supply, some Seed reading materials, and a complimentary travel vial that holds a week’s worth of your DS-01™, so you never miss a day on the go.
Why does my second month's shipment look different from the first?
Cool—you’ve met our sustainable refill system.
The planet is really important to us, so we’re constantly looking for materials that are sustainable, without sacrificing the safety and protection of your DS-01™. Our jars are made of glass, which is infinitely recyclable, but the less we put out there, the better. That’s why we ask you to keep your reusable glass jar and send you monthly refills instead.
All shipments—after your first—will come in a certified home-compostable, bio-based pouch that is oxygen and moisture resistant, while being planet-safe. It’s easy—just open the pouch and refill your jar.
Why do my DS-01™ capsules look different?
In May 2020, we made a minor update to the prebiotic blend in our DS-01™—Scandinavian chaga and pine bark were removed to accommodate an increased dosage of our primary prebiotic, punicalagin (from Indian pomegranate). Our 24-strain probiotic formulation is still encapsulated in the Probiotic Inner Capsule, which is nested in the now-powdered Prebiotic Outer Capsule.
While you may notice small cosmetic changes in your refill capsules, this has no impact on our clinically and scientifically studied benefits, and results from our continued close work with the FDA as we move our DS-01™ into upcoming clinical trials—the first will be conducted at Harvard Medical School – Beth Israel Deaconess to assess the clinical effects of our DS-01™ in treating Irritable Bowel Syndrome (IBS), and the second under Health Canada approval to study the DS-01™ and its impact on post-antibiotic recovery. These clinical trials reflect our continued commitment to R+D and deeper understanding and expansion of our products and their applications.
The prebiotic blend update also ensures we adhere to various international regulatory guidelines as we expand to a wider global community.
How do I sign up for a subscription?
Military, first responder, student, or teacher?
You inspire us—and we are honored to cover 15% of your subscription cost each month (for orders shipping to the US). To activate, simply navigate to checkout, then follow the prompts for a verification process through our partner, SheerID, to receive your unique code.
Should you have any questions or concerns about your verification status, kindly reach out to [email protected]. After verification, any questions about your DS-01™ or your subscription can be directed to [email protected]—or find us on Instagram.
I'm having trouble logging into my account.
Apologies for any confusion—we’ve migrated to a new platform so we may better serve you (and your microbes). To ensure your existing account is synced with our new platform, kindly reset your password and try again.
You’ll only need to do this once. We’re here to help—[email protected] if you have any questions.
How do I cancel my subscription?
I lost/broke my glass jar. How can I get a replacement?
I'm traveling—can I reschedule my next shipment?
Absolutely. Simply navigate to your account and reschedule your upcoming shipment for any date in the future. Once you do, we’ll automatically update any further monthly shipments.
Don’t forget to pack your travel vial. 😉
How do I review my orders, order history, or tracking information?
Shipping + Billing
One of my items arrived damaged. What do I do?
What payments do you accept?
Visa, MasterCard, American Express, Discover, and PayPal. We unfortunately cannot accept cash, checks, money orders, bitcoin, or hugs. 🙂
How much is shipping?
Shipping to the US: free
Shipping internationally: $10 flat rate (USD) (+ any local taxes and duties)
Can I return DS-01™?
There’s no need to send your DS-01™ back to us for a return. If for any reason you are not satisfied with your purchase, you may request a refund within 30 days of delivery of your first order. We’ll refund you for the full cost of the product less shipping, VAT, or duties—no questions asked. Refunds apply to your first order only, not any subsequent shipments, even if they are billed, paid, or shipped during this 30-day period. For all subsequent shipments, you may reschedule or cancel at any time in your account.
Will I be charged sales tax?
Shipping to the US: We are required to collect sales tax for orders shipping to the following states:
All other states are currently tax-free.
Shipping internationally: We ship DDP, meaning duties and taxes are paid up front, at checkout. Our global delivery partner, Passport Shipping, built a state-of-the-art shipping calculator that estimates duties and taxes before you place your first order. We will recalculate duties and taxes monthly, for each refill package. Kindly note, the price will typically remain the same unless there has been a change in your country’s government policy.
When will my credit card be charged?
You are billed each month when your subscription renews, using the payment method you have on file. This charge will occur approximately every 30 days, unless you cancel. You may view your next shipment date in your account.
How can I trust that my saved payment and personal information is secure?
Will my DS-01™ survive being shipped in the heat? What about the cold?
We’ve conducted extensive heat testing on our DS-01™—after 10 days of constant, 24 hour, 100º F exposure (which is highly unlikely even in the heat of summer), our probiotic bacteria counts and viability exceeded the living cell counts stated on our label.
DS-01™ is also fine in temperatures below freezing. In fact, freezing and below freezing temperatures are good at keeping the bacteria in an ideal state.
Depending on the temperature of your home (or where you are traveling), kindly follow the recommended storage guidelines.
Do you ship internationally?
How much is international shipping?
We offer a $10 USD flat rate shipping fee + any applicable local taxes/duties may apply.
Do you offer quarterly shipping?
After you receive your first DS-01™ order, which includes your reusable jar + travel vial, you may enroll into our Sustainable Transport Program for 90-day refills, billed every 3 months, shipped free (local taxes/duties still apply).
If you’d like to enroll into STP starting in your second month, kindly reach out to [email protected].
How long does international shipping take?
International orders generally arrive 7-14 business days after they’ve shipped.
I thought shipping was free when enrolled in STP—what is the additional charge?
Kindly note, when enrolled in STP, your shipping fee is automatically waived. A 3-month supply of the DS-01™ is $149.97 USD—any additional amount is local taxes/duties imposed by your local government.
We ship DDP, meaning duties and taxes are paid up front at checkout. We will recalculate duties and taxes for each shipment—the price will typically remain the same unless there has been a change in your country’s government policy.