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PDS-08™ Pediatric Daily Synbiotic is a clinically studied 2-in-1 powdered probiotic + prebiotic, formulated for children and adolescents ages 3-17 with 9 probiotic strains and a fiber-based prebiotic.

PDS-08™ Pediatric Daily Synbiotic is meant for children and adolescents ages 3–17, as this is the age group in which our product and probiotic strains have been evaluated for efficacy and tolerability.

PDS-08™ was formulated in a powdered format for several reasons—including ease of use in a pediatric population (children cannot easily swallow capsules) and the ability to incorporate a clinically meaningful dose of prebiotic fiber. Our powdered format also allows for the use of heat-sensitive probiotic strains (which would otherwise be damaged in the manufacturing of formats like gummy-based probiotics).

Probiotics and prebiotics, alongside foundational lifestyle factors, can provide support for a healthy microbial ecosystem.

Over the past decade, research has illuminated the significant role of the microbiome in a developing child and how factors like diet, exercise, environment, use of antibiotics, sleep, and hygiene can impact critical windows of development and inform their systemic health through adulthood. Alongside these factors, probiotics for adults, adolescents, and children have tremendous potential to modulate and support one’s health. Still, appropriate skepticism and confusion remain due to the plethora of unvalidated benefits marketed today. 

The best solution for you and your child depends on what benefits you’re looking for. While it’s true that today, most parents and caregivers are looking for a probiotic to support (or optimize) gastrointestinal function and digestive health, it’s important to first identify that probiotics are a science and that specific strains are studied for specific outcomes, even within those areas of impact. For example, certain strains have been studied in children to impact antibiotic-associated diarrhea, whereas others have been studied to support bowel movement frequency and ease of pooping. With approximately 11% of young children experiencing antibiotic-associated diarrhea, up to 29% of the pediatric population worldwide classified as clinically constipated, and 50% of children with constipation still having problems after 5 years of treatment, along with countless other children simply experiencing anxiety or strain related to pooping, there are millions of children on Earth who can benefit from the digestive and GI impact of clinically validated probiotics. 

But as the field of probiotics has advanced alongside our understanding of the critical role that the microbiome plays in a child’s developing immune and systemic health, we can now look to probiotics for benefits beyond digestion, especially the specific strains studied to support gut-immune function, gut barrier integrity, and even respiratory and skin health. 

An additional consideration is that our modern living practices and daily choices—such as more time spent indoors (and away from natural environments), poor diet, lack of fiber, antibiotic overuse, and other environmental factors—can disrupt the microbiome, especially in critical windows of development for children. For these reasons, and alongside critical levers like diet and nutrition, specific probiotics can be an impactful way to nurture and support your child’s microbiome and systemic health beyond digestion. 

PDS-08™ Pediatric Daily Synbiotic is formulated with probiotic strains that have been clinically studied to support gastrointestinal health, gut barrier integrity, gut-immune function, dermatological health, and respiratory health.

PDS-08™ was studied in a double blind, randomized, placebo controlled trial, in a pediatric population to support healthy bowel function in children with a low frequency of weekly bowel movements.  

The probiotic strains in PDS-08™ have been studied in various pediatric populations to support benefits for gut barrier integrity, gut-immune function, dermatological health, and respiratory health. The dosages in our product reflect the exact dose used in their respective clinical trials. 

Additionally, the composition was shown to significantly enrich Bifidobacterium in the pediatric gut microbiome (as demonstrated via metagenomic shotgun sequencing) and support the production of short-chain fatty acids (SCFAs) in vitro through the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®).

You can learn more about the science behind PDS-08™ in our Reference Library here.

There is no optimal time of day for your child to consume PDS-08™ Pediatric Daily Synbiotic—however, it’s often ideal at mealtime since consuming PDS-08™ with food is important for maximum viability. While probiotics are a science, parenting is not—however your child prefers to take PDS-08™ each day, that’s the best way.

Pick a time of day to start PDS-08™ with your child—you know your child’s routine best. It may be easiest to coincide with a mealtime (and  it’s optimal to consume PDS-08™ with food).

Take 1 sachet from your BacTrac™ container and pour it into a cold or room-temperature food or drink(Not hot, please.)

Mix well. Stir into food until fully mixed. If stirring into a drink, shake thoroughly in a closed bottle. Bacteria are fragile, so please no heat, blenders, or food processors, as these can impact the activity of the probiotics.

Enjoy within 30 minutes. Yes, this means all of it! As the probiotics and prebiotics are exposed to moisture, they activate and start to interact with one another. If left to sit for too long, this could lead to digestive discomfort after consumption.

Align the top of your BacTrac™ container with the day that you are starting. PDS-08™ doesn't require refrigeration, so feel free to store it on your countertop.

Repeat and track so you never miss a day.

PDS-08™ Pediatric Daily Synbiotic can be consumed with cold or room-temperature soft foods or liquids of choice. 

While there is no optimal food or beverage to consume PDS-08™ with, we recommend trying to find a method that consistently works best for the individual taking it. Some suggestions include: water, apple sauce, yogurt, fruit puree, overnight oats, or a plant-, nut- or animal-based milk of choice.

In testing, we found that mixing PDS-08™ into your child’s favorite soft foods yields optimal results. 

If you prefer to stir PDS-08™ into a drink, shake thoroughly in a closed bottle. Bacteria are fragile, so please no heat, blenders, or food processors as these can impact the activity of the probiotics.

When mixed in a flavorless food or drink like water, PDS-08™ Pediatric Daily Synbiotic has a mildly sweet taste due to the long-chain prebiotic fiber inulin, though no sugar or artificial sweeteners were added to the product. When mixed into soft foods or other beverages, your child may not notice any flavor at all.

1 sachet daily (or: 20 Billion AFU + 6g of prebiotic).

Each sachet contains 6.27g/0.22 oz of powder.

We suggest consuming the full daily dose of PDS-08™ Pediatric Daily Synbiotic within 30 minutes to ensure maximal potency of the product. 

We know how hard it is to find evidence-based information so we can make the best choices—especially for parents. Between flavored powders and brightly colored gummies, choosing a pediatric probiotic is a challenge.

So we developed PDS-08™ Pediatric Daily Synbiotic with science and simplicity in mind. PDS-08™ is a clinically studied 2-in-1 powdered probiotic and prebiotic with 9 probiotic strains and a dual-phase, mixed-chain-length, fiber-based prebiotic comprised of of inulin and fructooligosaccharides (FOS). The formulation offers 5g of prebiotic fiber in each serving, which helps parents incorporate this important nutrient into their child’s diet. PDS-08™ is sugar-free and easy to take on the go—no refrigeration required.

PDS-08™ is the first 9-strain synbiotic studied in a double-blind, randomized, controlled trial in a pediatric cohort shown to support gastrointestinal function and a healthy frequency of weekly bowel movements. It is also the first multi-strain synbiotic to include two pioneering strains clinically validated in children to support respiratory health and a healthy response to seasonal airborne particles. 

The probiotic strains in PDS-08™ have been studied in 18 clinical trials specifically conducted in various pediatric cohorts and the dosages in our product reflect the exact dose used in their respective clinical trials. This means that these strains have demonstrated a health benefit at an 'effective dosage' in the same dose included in our PDS-08™ formulation.

Lastly, PDS-08™ undergoes extensive testing (well beyond what’s required) throughout each step of the manufacturing process as well as on the final product. This includes testing for potency, survivability, contaminants (pesticides, mycotoxins, and heavy metals), and over 20 allergens defined by the European Food Safety Authority (EFSA).

PDS-08™ Pediatric Daily Synbiotic adheres to vegan, vegetarian, gluten-free, dairy-free, and peanut-free diets and is free of 14 classes and over 20 total allergens as defined by the European Food and Safety Authority (EFSA), including dairy, gluten, soy, corn, sesame seeds, soy, and nuts (almond, brazil, cashew, hazelnut, macadamia, peanut, pecan, pine, pistachio, and walnut). 

Additionally, PDS-08™ is sugar-free, glyphosate/AMPA-free, preservative-free, and Prop. 65-compliant.

In the double-blind, randomized, placebo-controlled trial on children ages 3–17 conducted on PDS-08™ Pediatric Daily Synbiotic, there were no observed side effects or GI distress (such as pain, bloating, gas, or diarrhea) as commonly reported with many fiber-based dietary supplements, probiotics, and high-dose fermentable prebiotics. 

However, every child is physiologically unique. If you know your child is prone to digestive sensitivity, we recommend starting and acclimating with half a sachet for the first few days. Simply store the unused half in an air-tight container or bag for use the following day. When your child is ready, increase to the full dose of 1 sachet, daily.

Each individual is physiologically unique, and the benefits one may “feel” (e.g., ease of bloating or easy, frequent poops) are often just the most visceral ones.

One may feel results in as little as 24–48 hours due to localized digestive support, though other longer-term benefits for gut-immune function or respiratory health may take longer or may not be tangibly noticeable, which is normal. As long as daily intake is continued, PDS-08™ is doing the work inside to program, sustain, and enhance your child’s health.

Yes—PDS-08™ Pediatric Daily Synbiotic is safe to take with other dietary supplements, though we always recommend checking with your pediatrician or physician.

There are no known contraindications with PDS-08™ Pediatric Daily Synbiotic and medications, therefore PDS-08™ would be generally safe to take alongside any prescription or over-the-counter medications.

However, we always recommend consulting with your doctor or family physician so they may advise with the complete knowledge of your child's health history.

As there are no known contraindications with PDS-08™ Pediatric Daily Synbiotic and medications, it is safe to take PDS-08™ while undergoing antibiotic therapy. However, we always recommend checking with your child’s doctor or pediatrician. 

While on a course of antibiotics, we do recommend spacing out when your child takes the antibiotic from PDS-08™ as far as possible—i.e., one in the morning and one in the evening.

During and after antibiotic use is a good time for probiotics, asnumerous studies have evaluated  a variety of strains and combinations of strains for their ability to mitigate GI distress during antibiotic use such asantibiotic-associated diarrhea (AAD). 

It's important to note, though, that probiotics are beneficial organisms that are also susceptible to being killed off by antibiotics—especially broad-spectrum antibiotics, which is why we generally recommend trying to separate intake as much as possible if they are to be taken at the same time.

It is safe to consume more than the recommended daily dose of 1 sachet, though there is not necessarily any added benefit in doing so. It is also important to note that because our prebiotic formulation is fermentative, your child could experience some mild to moderate gastrointestinal upset at a higher dose.

Simply store PDS-08™ Pediatric Daily Synbiotic at room temperature in the aluminum BacTrac™ container provided in your Welcome Kit. 

There is no refrigeration necessary.

Though many probiotics are sold in the refrigerated section at grocery stores and other retailers, refrigeration doesn’t necessarily mean “freshness” or superiority. In fact, if a probiotic does not survive at ambient temperature outside of the refrigerator, it can reflect weak stability of the product, low viable organism count, or inadequate overages in formulation.

Each daily dose of PDS-08™ is sealed in an individual biofilm sachet, further protecting the probiotics from environmental elements. For optimal viability, we do recommend storing in a cool, dry area.Consider refrigerating only if your home is consistently warmer than room temperature (>79° F/26° C) for extended periods.

PDS-08™ Pediatric Daily Synbiotic is shelf-stable for 18 months past the manufacturing date. 

You can find the expiration date printed in black on the back of each sachet.

While PDS-08™ is safe to take past expiration, we can only guarantee potency and viability up until the expiration date.

There’s no harm in missing a day, or even a few, but daily intake is important for optimal results. This is because, in general, probiotics are transient microbes, which means they travel through the digestive tract interacting with immune cells, gut cells, dietary nutrients, and existing microbes along the way (to trigger local and systemic benefits), before eventually exiting the body. This is why continuous, daily intake is important.

Probiotics, in general, are transient microbes—which means they trigger both local and systemic benefits as they travel through the digestive tract interacting with immune cells, gut cells, dietary nutrients, and existing microbes along the way before eventually exiting the body. Science has demonstrated that the benefits conferred by these transient organisms are confined to the duration of consumption or shortly thereafter, which indicates that their efficacy is dependent on continuous use. Therefore, if sustained benefits are desired, continuous, daily intake is important.

Due to the importance of consistency, we offer PDS-08™ Pediatric Daily Synbiotic on a subscription basis.

Each month, you will receive a 30-day supply (30 individual sachets) of PDS-08™ Pediatric Daily Synbiotic, which can be safely stored in your refillable BacTrac™ container for an additional layer of protection from light and moisture.

Your BacTrac™ container was also designed to track daily use. Simply twist the container top to align the dot (•) and day so you always remember the last date of use.

PDS-08™ Pediatric Daily Synbiotic is a 2-in-1 probiotic and prebiotic formulated with 9 probiotic strains and a fiber-based prebiotic composed of inulin and FOS (fructooligosaccharides).

PDS-08™ is free from sugar, artificial colorants, flavors, flow agents, binders, preservatives, and 14 classes of allergens.

You may view our complete strain list and included ingredients here.

Just as with any new diet, product, or lifestyle change, your child may experience a temporary acclimation period when first starting PDS-08™ Pediatric Daily Synbiotic. This can include some gastrointestinal discomfort, abdominal tightness, mild nausea, or changes in their stool. This is normal. 

In fact, an immediate physiological reaction is a sign that our probiotics are viable and attuning to your child’s system as they move throughout the gastrointestinal tract. Any discomfort should subside within the first few weeks of consistent daily use.

If you know your child is prone to digestive sensitivity, we recommend starting with half a sachet for the first few days. When your child is ready, increase to the full dose of 1 sachet, daily.

In the United States, dietary supplements are not reviewed or approved by the FDA for safety or efficacy. However, the FDA does regulate and enforce associated claims for both dietary supplements (the finished products) and dietary ingredients (the individual constituents that comprise dietary supplements). Our PDS-08™ Pediatric Daily Synbiotic adheres to all FDA established regulations for dietary supplements (current Good Manufacturing Practices, or “cGMP”) and all of its ingredients meet the definition of an allowed dietary ingredient. PDS-08™ also exceeds U.S. regulations for ingredient and finished product testing and meets the highest global regulatory standards in Europe (EFSA) and Japan (FOSHU). Lastly, the FDA requires that claims made for each dietary supplement are backed by credible and systematic scientific investigations. PDS-08™ enjoys 18 clinical studies on its probiotic strains and has been subjected to a placebo-controlled randomized trial to evaluate its effect on bowel movement frequency.

Our PDS-08™ Pediatric Daily synbiotic undergoes extensive testing throughout each step of the manufacturing process as well as on the final product. This includes whole-genome sequencing on our strains (translation: we know which strains are present and in which quantities), flow cytometry (flow cytometry measures Active Fluorescent Units—a more accurate way of measuring all viable cells), survivability testing to ensure the optimal conditions for our probiotics to survive transit through the GI tract, heat and humidity testing to mimic the most extreme conditions our product may encounter during shipping and storage, and over 50 quality-assurance and quality-control (QA/QC) checkpoints.

The final product is tested for 420 different pesticides (including glyphosate) and over 20 of the most common allergens as defined by the European Food Safety Authority (EFSA). Our probiotic strains have GRAS and/or QPS status, which designates them as safe for consumption by the United States and European Union, respectively.

We monitor purity under both U.S. and European protocols (including cGMP + HACCP) throughout the production cycle with lot-to-lot testing (this means we test each ingredient batch prior to encapsulation and each batch after manufacture).