DS-01®
Daily Synbiotic

For Adults (18+)

Probiotic and prebiotic formulated to provide benefits for gut immune function and whole-body health for adults ages 18+.

53.6 Billion AFU

$49.99
30 day supply.
$49.99 per subscription, billed monthly.
CHOOSE YOUR SCHEDULE
Delivered every month

Sustainably delivered, monthly.

Each component of our refill system is designed to protect your DS-01® and be gentler on our Earth.

Month 1 — Welcome Kit

  • Refillable Glass Jar

  • Glass Travel Vial

  • 30 Day Supply (60 Capsules)

Month 2 — Sustainable Refills

  • 30 Day Supply (60 Capsules)

Why Seed Members Love DS-01®

”It’s really helping my daily bowel movements and keeping me regular.”

”It’s really helping my daily bowel movements and keeping me regular.”

JILLIAN E.

“I felt really good throughout the day. I became regular. In about two weeks after taking it, I wasn't bloated.”

“I felt really good throughout the day. I became regular. In about two weeks after taking it, I wasn't bloated.”

CAMERON B.

“The first thing I do when I get up in the morning is have my Seed with water. And then I poop, and I just feel great.”

“The first thing I do when I get up in the morning is have my Seed with water. And then I poop, and I just feel great.”

ALICE V.

“I immediately noticed how much lighter I felt around my belly. It really helps me stay regular, and you’re not bloated at all.”

“I immediately noticed how much lighter I felt around my belly. It really helps me stay regular, and you’re not bloated at all.”

ZAM T.

Promotes digestive health (to support healthy regularity and ease of bloating)*

Reinforces healthy stool hydration and ease of evacuation*

Supports gut ease from occasional gastrointestinal discomfort associated with increased intestinal transit time*

Gut Barrier Integrity

Maintains healthy gut barrier function and integrity*

Reinforces healthy tight junction in vitro*

Supports healthy gut barrier integrity from ethanol- and endotoxin-induced (lipopolysaccharide) permeability in vitro*

Gut Immune Function

Supports healthy gut immune function and 'cross-talk' between immune and intestinal cells*

Maintains healthy immunological responses in the gastrointestinal tract*

Supports production of short-chain fatty acids*

Cardiovascular Health

Promotes heart health*

Maintains blood cholesterol levels already in the normal range*

Supports healthy intestinal recycling of cholesterol and bile*

Dermatological Health

Promotes healthy skin*

Reinforces healthy gut-skin axis*

Supports folate (vitamin B9) production via intestinal synthesis of bioactive forms of folate*

Supports synthesis of vitamin B12 in vitro*

Benefits beyond
your gut.

Formulated with strains that support:

Promotes digestive health (to support healthy regularity and ease of bloating)*

Reinforces healthy stool hydration and ease of evacuation*

Supports gut ease from occasional gastrointestinal discomfort associated with increased intestinal transit time*

Maintains healthy gut barrier function and integrity*

Reinforces healthy tight junction in vitro*

Supports healthy gut barrier integrity from ethanol- and endotoxin-induced (lipopolysaccharide) permeability in vitro*

Supports healthy gut immune function and 'cross-talk' between immune and intestinal cells*

Maintains healthy immunological responses in the gastrointestinal tract*

Supports production of short-chain fatty acids*

Promotes heart health*

Maintains blood cholesterol levels already in the normal range*

Supports healthy intestinal recycling of cholesterol and bile*

Promotes healthy skin*

Reinforces healthy gut-skin axis*

Supports folate (vitamin B9) production via intestinal synthesis of bioactive forms of folate*

Supports synthesis of vitamin B12 in vitro*

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Engineered to
survive

ViaCap® Delivery Technology

Our 2-in-1 nested capsule safeguards viability through digestion to deliver the maximum starting dose to your colon. The outer capsule also serves as a barrier to oxygen, moisture, and heat–no refrigeration necessary.

Probiotic Inner Capsule

Our probiotic formulation consists of clinically and scientifically studied strains characterized at academic institutions and research partners in Italy, Spain, Belgium, US, and Japan. It is biofermented in Europe, and is not of animal or soil origin.

Prebiotic Outer Capsule

Our prebiotic formulation consists of punicalagins concentrated from Indian pomegranate—biotransformed by gut microbes into powerful metabolites for human health.

Not All Probiotics Are Created Equal
DS-01® is formulated with 24 strains not commonly found in other probiotics or foods.
DS-01™OTC ProbioticsFermented Food + Drinks
Potent strains with verified health benefits (53.6B AFU)RareRare
24 strains for whole-body health
Engineered to survive digestionRare
View All

Formulation

53.6 Billion AFU
No refrigeration required.

Probiotic Inner Capsule
Probiotic Inner Capsule

Our probiotic formulation consists of clinically and scientifically studied strains characterized at academic institutions and research partners in Italy, Spain, Belgium, US, and Japan. It is biofermented in Europe, and is not of animal or soil origin.

Bifidobacterium longum SD-BB536-JP 

Bifidobacterium breve SD-BR3-IT 

Lactiplantibacillus plantarum SD-LP1-IT 

Lacticaseibacillus rhamnosus SD-LR6-IT 

Lacticaseibacillus rhamnosus HRVD113-US 

Bifidobacterium infantis SD-M63-JP 

Bifidobacterium lactis SD-BS5-IT 

Bifidobacterium lactis HRVD524-US 

Lactobacillus crispatus SD-LCR01-IT 

Lacticaseibacillus casei HRVD300-US 

Bifidobacterium breve HRVD521-US 

Bifidobacterium longum HRVD90b-US 

Bifidobacterium lactis SD150-BE 

Limosilactobacillus fermentum SD-LF8-IT 

Lacticaseibacillus rhamnosus SD-GG-BE 

Limosilactobacillus reuteri RD830-FR

Ligilactobacillus salivarius SD-LS1-IT

Bifidobacterium lactis SD-CECT8145-SP

Bifidobacterium longum SD-CECT7347-SP

Lacticaseibacillus casei SD-CECT9104-SP

Lactiplantibacillus plantarum SD-LPLDL-UK

Bifidobacterium lactis SD-MB2409-IT

Bifidobacterium adolescentis SD-BA5-IT

Limosilactobacillus reuteri SD-LRE2-IT

Indian Pomegranate [whole fruit] (Punica granatum) (>40% Polyphenolic + Phenolic Bioactives)

Prebiotic Outer Capsule
Prebiotic Outer Capsule

Our prebiotic formulation consists of punicalagins concentrated from Indian pomegranate—biotransformed by gut microbes into powerful metabolites for human health.

Acid-Resistant Vegan Outer [chlorophyllin] and Inner Capsules [hypromellose, fermented gellan gum, water] 

Organic rice fiber 

Organic rice extract blend

Bifidobacterium longum SD-BB536-JP 

Bifidobacterium breve SD-BR3-IT 

Lactiplantibacillus plantarum SD-LP1-IT 

Lacticaseibacillus rhamnosus SD-LR6-IT 

Lacticaseibacillus rhamnosus HRVD113-US 

Bifidobacterium infantis SD-M63-JP 

Bifidobacterium lactis SD-BS5-IT 

Bifidobacterium lactis HRVD524-US 

Lactobacillus crispatus SD-LCR01-IT 

Lacticaseibacillus casei HRVD300-US 

Bifidobacterium breve HRVD521-US 

Bifidobacterium longum HRVD90b-US 

Bifidobacterium lactis SD150-BE 

Limosilactobacillus fermentum SD-LF8-IT 

Lacticaseibacillus rhamnosus SD-GG-BE 

Limosilactobacillus reuteri RD830-FR

Ligilactobacillus salivarius SD-LS1-IT

Bifidobacterium lactis SD-CECT8145-SP

Bifidobacterium longum SD-CECT7347-SP

Lacticaseibacillus casei SD-CECT9104-SP

Lactiplantibacillus plantarum SD-LPLDL-UK

Bifidobacterium lactis SD-MB2409-IT

Bifidobacterium adolescentis SD-BA5-IT

Limosilactobacillus reuteri SD-LRE2-IT

Indian Pomegranate [whole fruit] (Punica granatum) (>40% Polyphenolic + Phenolic Bioactives)

Acid-Resistant Vegan Outer [chlorophyllin] and Inner Capsules [hypromellose, fermented gellan gum, water] 

Organic rice fiber 

Organic rice extract blend

VeganVegan
Gluten-testedGluten-tested
Dairy-testedDairy-tested
Soy-testedSoy-tested
Nuts-testedNuts-tested
Shellfish-testedShellfish-tested
Sesame-testedSesame-tested
Glyphosate/AMPA-testedGlyphosate/AMPA-tested
Corn-testedCorn-tested
No BindersNo Binders
No PreservativesNo Preservatives
Prop. 65 CompliantProp. 65 Compliant

A new standard in probiotics.

Survivability

Probiotics are most effective when they make it to your colon, alive. Our ViaCap®️ technology ensures bacteria survive and stay viable through digestion. Bonus: no synthetic or chemical coating and no refrigeration required.

Biofermentation

How bacteria are cultured impacts their viability. We optimize our biofermentation for pH, temperature, and 28 other critical growth factors. Our mediums contain no meat or dairy.

Testing

We do extensive no-skip-lot testing at each step of the manufacturing process as well as on the final product. With 50+ quality assurance and quality control (QA/QC) checkpoints, we monitor purity under both US and European protocols (including cGMP + HACCP) throughout the production cycle.

Survivability
Testing
Biofermentation
BiofermentationSurvivabilityTesting

Survivability

Probiotics are most effective when they make it to your colon, alive. Our ViaCap®️ technology ensures bacteria survive and stay viable through digestion. Bonus: no synthetic or chemical coating and no refrigeration required.

SurvivabilityBiofermentationTesting

Biofermentation

How bacteria are cultured impacts their viability. We optimize our biofermentation for pH, temperature, and 28 other critical growth factors. Our mediums contain no meat or dairy.

SurvivabilityTestingBiofermentation

Testing

We do extensive no-skip-lot testing at each step of the manufacturing process as well as on the final product. With 50+ quality assurance and quality control (QA/QC) checkpoints, we monitor purity under both US and European protocols (including cGMP + HACCP) throughout the production cycle.

Sustainably delivered, monthly.

Each component of our refill system is designed to protect your DS-01® and be gentler on our Earth.

Month 1 — Welcome Kit

  • Refillable Glass Jar

  • Glass Travel Vial

  • 30 Day Supply (60 Capsules)

Month 2 — Sustainable Refills

  • 30 Day Supply (60 Capsules)

For the curious.

Adults—take 2 capsules daily, all at once. Preferably on an empty stomach to limit exposure to digestive enzymes and bile salts. However, you know your body best—if it’s more comfortable for you to take with food, please feel free to do so.

You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. They perform critical functions like digesting food, managing inflammation, and synthesizing key vitamins, metabolites and neurotransmitters. This is the microbiome.

DS-01® is a probiotic and prebiotic formulated to provide benefits for gut immune function and whole-body health for adults ages 18+.

DS-01® contains probiotic strains that have been clinically and scientifically studied to provide benefits around gastrointestinal function, skin health, heart health, gut immune function, gut barrier integrity, and micronutrient synthesis. You may access the strain-specific clinical studies associated with each benefit in our Reference Library.

Everyone’s body is different, and the benefits you may ‘feel’ (ease of bloating, more regular bowel movements) are often just the most visceral ones.

It is normal to feel effects in the digestive tract in as little as 24-48 hours. Other longer term benefits like cardiovascular health and gut immune function may take longer, or you may not notice anything at all. That’s completely normal. As long as you continue your daily intake, those beneficial microbes are doing their work inside to program, sustain, and enhance your health.

DS-01® is meant for humans ages 18+.

DS-01® is tested for: Dairy, Gluten, Soy, GMOs, Nuts, Shellfish, Sesame, Glyphosate/AMPA, and 14 classes of allergens defined by European Food and Safety Authority (EFSA)

It adheres to the following diets: Vegan • Vegetarian • Ketogenic • Gluten-Free • Intermittent Fasting

DS-01® is safe to take with other supplements.

There are no known contraindications with DS-01® and any over the counter or prescription medications, though we encourage you to double check with your physician before adding our product to your regimen.

As with any dietary supplement or new health protocol contemplated during pregnancy or lactation, we recommend speaking with your physician or obstetrician before you start consuming DS-01® Daily Synbiotic.

Probiotics, in general, do not appear to pose any safety concerns for pregnant and lactating individuals. The current literature does not indicate an increase in adverse pregnancy outcomes when probiotics are used by healthy individuals.

The short answer is no. No refrigeration necessary.

It’s a question we receive often, since many probiotics are sold in the refrigerated section at grocery stores and retailers. However, contrary to perishable food products, refrigeration doesn’t mean "freshness" or superiority. In fact, if a probiotic does not survive at ambient temperature outside of the refrigerator, it can reflect weak stability of the product, low viable organism count, or inadequate overages in formulation.

If your home is consistently warmer than 79° F for extended periods, consider refrigerating in an oxygen tight container to avoid exposure to moisture.

Your monthly subscription includes a 30-day supply of DS-01®. Your first month’s shipment is your Welcome Kit. It includes a reusable glass jar holding your first month’s supply, some Seed reading materials, and a complimentary travel vial that holds a week’s worth of your DS-01®, so you never miss a day on the go.

Yes. We believe that probiotics and prebiotics, alongside diet, nutrition, exercise, and lifestyle, are cornerstone tools to building foundational health. Clinical research shows that continuous, daily intake is the best way to get the most out of your synbiotic. By signing up for a subscription, you’ll easily be able to build DS-01® into your routine.

But we want you to feel good about what you’re taking. That’s why we want you to try DS-01®, risk-free for 30 days. You may also reschedule or cancel your subscription easily from your account at any time.

If for any reason you are not satisfied with your purchase, you may request a refund within 30 days of delivery of your first order. We’ll refund you for the full cost of the product less shipping, VAT, and duties—no questions asked. Refunds apply to your first order only, not any subsequent shipments. For all subsequent shipments, you may reschedule or cancel at any time in your Account.

Kindly note that Sustainable Refill Program orders are considered final sale 30 days after delivery.

Yes—find out more at seed.com/entire-world

Yes.