Dr. Maurizio Fava is the Executive Vice Chair of the Department of Psychiatry, Executive Director of the MGH Clinical Trials Network & Institute (CTNI) and Director of Clinical Research at Massachusetts General Hospital. Dr. Fava is also Associate Dean for Clinical and Translational Research and Slater Family Professor of Psychiatry at Harvard Medical School. Dr. Fava served as co-principal investigator of the STAR*D study, the largest study ever conducted in the field of depression; the findings were published in over 120 papers published in journals such as NEJM and JAMA. In addition to his numerous clinical trials and studies in treatment resistant depression, Dr. Fava has contributed significantly to the field of psychiatric research in a number of other areas. Dr. Fava has authored or co-authored more than 800 original articles, has also edited eight books, and he has published more than 100 chapters/reviews and over 500 abstracts. Dr. Fava’s work has been cited more than 70,000 times in the literature, with an h index of over 120. He has received several awards including the Distinguished Fellow Award from the American Psychiatric Association and is on the editorial board of four international medical journals.

Over the past 24 years, Dr. Fava has also been successful in obtaining over $60,000,000 in funding for his program, as principal or co-principal investigator, from the National Institute of Health, other federal agencies, and foundations.

Key publications:

Reduced caudate and nucleus accumbens response to rewards in unmedicated individuals with major depressive disorder Diego A Pizzagalli, Avram J Holmes, Daniel G Dillon, Elena L Goetz, Jeffrey L Birk, Ryan Bogdan, Darin D Dougherty, Dan V Iosifescu, Scott L Rauch, Maurizio Fava American Journal of Psychiatry 166 (6), 702-710 (2009)

Difference in treatment outcome in outpatients with anxious versus nonanxious depression: a STAR* D report Maurizio Fava, A John Rush, Jonathan E Alpert, GK Balasubramani, Stephen R Wisniewski, Cheryl N Carmin, Melanie M Biggs, Sidney Zisook, Andrew Leuchter, Robert Howland, Diane Warden, Madhukar H Trivedi American Journal of Psychiatry 165 (3), 342-351 (2008)

Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR* D report A John Rush, Madhukar H Trivedi, Stephen R Wisniewski, Andrew A Nierenberg, Jonathan W Stewart, Diane Warden, George Niederehe, Michael E Thase, Philip W Lavori, Barry D Lebowitz, Patrick J McGrath, Jerrold F Rosenbaum, Harold A Sackeim, David J Kupfer, James Luther, Maurizio Fava American Journal of Psychiatry 163 (11), 1905-1917 (2006)

Evaluation of outcomes with citalopram for depression using measurement-based care in STAR* D: implications for clinical practice Madhukar H Trivedi, A John Rush, Stephen R Wisniewski, Andrew A Nierenberg, Diane Warden, Louise Ritz, Grayson Norquist, Robert H Howland, Barry Lebowitz, Patrick J McGrath, Kathy Shores-Wilson, Melanie M Biggs, GK Balasubramani, Maurizio Fava, Star* D Study Team American journal of Psychiatry 163 (1), 28-40 (2006)

Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression A John Rush, Madhukar H Trivedi, Stephen R Wisniewski, Jonathan W Stewart, Andrew A Nierenberg, Michael E Thase, Louise Ritz, Melanie M Biggs, Diane Warden, James F Luther, Kathy Shores-Wilson, George Niederehe, Maurizio Fava New England Journal of Medicine 354 (12), 1231-1242 (2006)

Diagnosis and definition of treatment-resistant depression M Fava Biological psychiatry 53 (8), 649-659 (2003)

Residual symptoms in depressed patients who respond acutely to fluoxetine. Andrew A Nierenberg, Bronwyn R Keefe, Vinita C Leslie, Jonathan E Alpert, Joel A Pava, John J Worthington III, Jerrold R Rosenbaum, Maurizio Fava The Journal of clinical psychiatry (1999)

Definition and epidemiology of treatment-resistant depression M Fava, KG Davidson Psychiatric Clinics of North America 19 (2), 179-200 (1996)